The method of preparation of 2-amino-5-nitrothiazole storage conditions and the calculation of chemical data

2-amino-5-nitrothiazole storage conditions

2-amino-5-nitrothiazole storage conditions are a white or light pink crystalline powder. It is easily soluble in ethanol, ethyl ether, benzene, trichloromethane, petroleum ether, and soluble in about 200 parts of water, and its solution is red when it meets ferrite salt. Today, Hebi Sake Chemical Co., LTD., a manufacturer of 2-amino-5-nitrothiazole storage conditions, will show you how to equip 2-amino-5-nitrothiazole storage conditions and calculate the chemical data.

It is produced by the reaction of pyridine with ferric chloride. Mixing 70g anhydrous pyridine with 13g anhydrous ferric chloride was heated in a sealed tube at 300℃ for about 35h. After cooling, the reactants solidify into red-black crystals. Open the sealing tube and wash out the red-black solution of the solid with a little hot water. The oily impurity is removed by ether extraction. After neutralization with sodium bicarbonate, excess pyridine is removed by steam heating. The mixture is then adjusted to a strong base and steam out 2,2'-2-amino-5-nitrothiazole storage conditions. After acidification, the product is evaporated and concentrated, and then sodium hydroxide is added. The product is extracted with ether, and the ether is removed to obtain crude product. The crude product is recrystallized with B, and the activated carbon is decolorized. In addition, the product can also be prepared by the reaction of α-methylpyridine [109-06-8] with potassium permanganate and purified treatment.

Computational chemical data editing

1. Reference value for calculating hydrophobic parameters (XlogP) : None

2. Number of hydrogen bond donors :0

3. Number of hydrogen bond receptors :2

4. Number of rotatable bonds :1

5. Number of tautomers: None

6. Topological molecular polar surface area 25.8

7. Number of heavy atoms :12

8. Surface charge :0

9. Complexity :120

10. Number of isotope atoms :0

11. Determine the number of primary constitutive centers :0

12. Number of indeterminate atomic orthostatic centers :0

13. Determine the number of chemical bond structure centers :0

14. Number of uncertain bond structure centers :0

15. Number of covalent bond units :1

2-amino-5-nitrothiazole storage conditions